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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
37.58
Human Site:
Y188
Identified Species:
55.11
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
Y188
W
G
L
N
K
Q
G
Y
Q
C
R
Q
C
N
A
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
Y188
W
G
L
N
K
Q
G
Y
Q
C
R
Q
C
N
A
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
Y651
W
G
L
N
K
Q
G
Y
K
C
R
Q
C
N
A
Dog
Lupus familis
XP_849292
706
81555
Y188
W
G
L
N
K
Q
G
Y
Q
C
R
Q
C
N
A
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
Y188
W
G
L
N
K
Q
G
Y
Q
C
R
Q
C
N
A
Rat
Rattus norvegicus
Q9WTQ0
707
81732
Y188
W
G
L
N
K
Q
G
Y
Q
C
R
R
C
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
Y188
W
G
L
N
K
Q
G
Y
Q
C
R
Q
C
N
A
Chicken
Gallus gallus
NP_001006133
699
80179
Y185
W
G
L
N
K
Q
G
Y
K
C
R
Q
C
N
A
Frog
Xenopus laevis
Q7LZQ8
671
76506
M170
A
E
I
K
E
E
V
M
T
V
T
V
G
D
A
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
K180
T
V
S
I
K
E
A
K
N
L
V
P
M
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
L175
Y
G
L
I
K
Q
G
L
Q
C
E
T
C
G
M
Honey Bee
Apis mellifera
XP_394743
624
71014
Y169
K
Q
S
E
N
T
I
Y
L
R
E
R
F
K
V
Nematode Worm
Caenorhab. elegans
P34722
704
80280
Y194
W
G
L
N
K
Q
G
Y
Q
C
Q
L
C
S
A
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
T169
V
N
N
Y
K
S
P
T
F
C
D
H
C
V
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
H382
I
L
L
T
L
G
F
H
K
S
S
Q
I
E
R
Red Bread Mold
Neurospora crassa
P87253
1142
127954
C486
K
Y
S
A
G
M
Q
C
E
D
C
K
Y
T
C
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
93.3
100
N.A.
100
93.3
N.A.
100
93.3
6.6
6.6
N.A.
53.3
6.6
80
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
33.3
20
N.A.
60
13.3
93.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
7
0
0
0
0
0
0
0
63
% A
% Cys:
0
0
0
0
0
0
0
7
0
69
7
0
69
0
13
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
7
0
0
13
0
% D
% Glu:
0
7
0
7
7
13
0
0
7
0
13
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
7
0
7
0
0
0
7
0
0
% F
% Gly:
0
63
0
0
7
7
63
0
0
0
0
0
7
7
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% H
% Ile:
7
0
7
13
0
0
7
0
0
0
0
0
7
0
0
% I
% Lys:
13
0
0
7
75
0
0
7
19
0
0
7
0
7
0
% K
% Leu:
0
7
69
0
7
0
0
7
7
7
0
7
0
0
0
% L
% Met:
0
0
0
0
0
7
0
7
0
0
0
0
7
0
7
% M
% Asn:
0
7
7
57
7
0
0
0
7
0
0
0
0
50
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
7
% P
% Gln:
0
7
0
0
0
63
7
0
50
0
7
50
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
50
13
0
0
7
% R
% Ser:
0
0
19
0
0
7
0
0
0
7
7
0
0
7
0
% S
% Thr:
7
0
0
7
0
7
0
7
7
0
7
7
0
7
0
% T
% Val:
7
7
0
0
0
0
7
0
0
7
7
7
0
7
7
% V
% Trp:
57
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
7
0
0
0
63
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _